There are three types of whey protein isolates: ion-exchange, cold-filtration and micro-filtration. These isolates are protein powders that are the next steps to further process whey protein concentrate. These different processes yield a higher protein content product because the fat and lactose are virtually removed. Whey protein isolates, because of their “purer protein form” are assimilated and digested through the intestines much quicker than whey protein concentrate. Because of this, whey protein isolates are best taken immediately after a workout because of the fast uptake of protein to the muscles.

A good supplement program is to use whey protein concentrate throughout the day before or with your meals when quick digestion isn’t required, and then use a whey protein isolate after your workouts when quicker digestion is required. Keep in mind, all whey protein supplements are digested relatively quickly, it’s just that whey protein isolates are digested even faster than whey protein concentrate. Isolates are also a better choice if you experience bloating and gas with whey protein concentrate.

If you want a slow digesting protein, consider using casein protein.  Casein is the perfect protein to take first thing in the morning and right before bed because it takes the body several hours to fully digest it. My protein supplement program looks like this:  I take a 50/50 blend of casein protein and whey protein concentrate first thing in the morning. Throughout the day in between meals I take a whey protein concentrate.  After my workout, I take whey protein isolate.  Finally, right before bed I take casein protein.

Ion-Exchange Whey Protein Isolate
This isolate is made by taking a whey protein concentrate and running it through what is called an “ion exchange” column to get an “ion exchange whey protein isolate.” While this process yields a higher protein content product (around 96%) with virtually no fat or lactose, many of the most important sub fractions are lost or greatly reduced. To experience the numerous health benefits of whey protein, you need the sub fractions untouched. Many supplement companies tout that they use “ion-exchange isolates” but that isn’t necessarily a good thing as you can see. I personally don’t use ion-exchange isolates because the sub fractions are removed. You can get a high protein content product without the sub fractions removed by using a cold-filtration or micro-filtration whey protein isolate.

Cold-Filtration & Micro-Filtration Whey Protein Isolates
Cold filtration is a process where the proteins are separated through the use of micro filtering the mass all while using a cold or "chilled" environment.

Microfiltration is a process where the proteins are separated through the use of natural ceramic filters. Microfiltrated whey protein isolates are left with more calcium and have the highest level of undenatured protein available.

Both of these processes result in a final product that is very high in protein content (greater than 90%), with virtually no undenatured protein with extremely low fat and lactose content (virtually fat-free and lactose free) – while retaining the important sub fractions.

Whey protein isolates also have a very clean taste and are excellent choices if you don’t like the taste of “protein powders.”

Other whey protein related pages:

What is Whey Protein?
Whey Protein Concentrate
Hydrolyzed Whey Protein
Benefits of Whey Protein
Whey Protein Side Effects
Whey Protein Articles
Whey Protein Reviews & Recommendations